Minkowitz is known for intricate pen-and-ink drawings, collages, crocheted wall works and three-dimensional mixed media sculptures. Her work is included in the permanent collections of the Metropolitan Museum of Art, New York, New York, Renwick Gallery, National Museum of American Art, Smithsonian Institution, Washington, D.C., Museum of Arts and Design, New York, New York, Montreal Museum of Fine Arts, Canada, Philadelphia Museum of Art, Pennsylvania and the Wadsworth Atheneum, Hartford, Connecticut.